Rung Five
Supplements
Unclear

Guggul

Commiphora resin, guggulsterones. Herbs & mushrooms.

Also called or includes: Guggulsterones, Commiphora mukul

Verdict
UnclearThere isn't enough human evidence to say either way.
How sure
Rung 1 · UnprovenLab or animal data only, or never directly tested in people.

The rung shows how sure the science is, not how big the effect is. How to read these ratings

Cancers affected

None shown in people

What the evidence shows

Lab and animal studies suggest guggulsterone may slow tumors; no human cancer trials have been done. In lab studies it switched on estrogen and progesterone receptors.

What to do

Not a cancer treatment. Ask your care team first: it may make some medicines less effective, and its hormone effects are a concern with hormone-sensitive cancers. Liver injury has been reported.

Sources

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Related

Every supplement we rated, or follow one cancer step by step: breast cancer, colorectal cancer, lung cancer and prostate cancer.