Unclear
Urolithin A
made by gut bacteria from pomegranates and berries; sold as pills. Longevity & fitness.
- Verdict
- UnclearThere isn't enough human evidence to say either way.
- How sure
- Rung 1 · UnprovenLab or animal data only, or never directly tested in people.
The rung shows how sure the science is, not how big the effect is. How to read these ratings
Cancers affected
None shown in people
What the evidence shows
A 2026 systematic review of urolithin A and colorectal cancer found only lab studies on cancer cells (15 of them) and said human trials are needed. Pomegranate juice itself is rated separately.
What to do
No reason to take it for cancer. Pomegranate and berries are fine as foods.
Sources
To take it to your doctor, print this page.
Spotted an error? Tell us and we’ll check it against the sources.
Related
Every supplement we rated, or follow one cancer step by step: breast cancer, colorectal cancer, lung cancer and prostate cancer.