Rung Five
Supplements
Unclear

Low-dose naltrexone

an addiction drug prescribed off-label at low doses. Sold as cures.

Also called or includes: LDN

Verdict
UnclearThere isn't enough human evidence to say either way.
How sure
Rung 1 · UnprovenLab or animal data only, or never directly tested in people.

The rung shows how sure the science is, not how big the effect is. How to read these ratings

Cancers affected

None shown in people

What the evidence shows

A 2022 review found consistent lab and animal results but called the evidence in people scarce and of poor quality: mostly case reports and case series, often combined with other remedies, and one 10-person study alongside immunotherapy. It called for proper randomized trials.

What to do

Not a proven cancer treatment. Ask your oncologist before taking it, especially if you take opioid painkillers, which it blocks.

Sources

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Related

Every supplement we rated, or follow one cancer step by step: breast cancer, colorectal cancer, lung cancer and prostate cancer.