Rung Five
All evidence
Rung 4 · Strong

Pembrolizumab with chemotherapy for early triple-negative breast cancer

Longer survival in a large randomized trial.

TreatmentWith your doctor

What studies found

In KEYNOTE-522 (1,174 patients), pembrolizumab given with chemotherapy before surgery and alone after surgery raised five-year overall survival to 86.6% from 81.7% with chemotherapy alone.

The catch

Based on one large trial.

What to do

If you have stage II or III triple-negative breast cancer, ask about it before treatment starts.

Sources

Rung 4 of 5, Strong: At least one large randomized trial, or very large consistent studies, on this exact question. How we score

To take it to your doctor, print this page.

Step by step

For the whole picture, from prevention and screening to treatment and life after, see the breast cancer page.

Related

Every option we rated