Pembrolizumab with chemotherapy for early triple-negative breast cancer
Longer survival in a large randomized trial.
What studies found
In KEYNOTE-522 (1,174 patients), pembrolizumab given with chemotherapy before surgery and alone after surgery raised five-year overall survival to 86.6% from 81.7% with chemotherapy alone.
The catch
Based on one large trial.
What to do
If you have stage II or III triple-negative breast cancer, ask about it before treatment starts.
Sources
Rung 4 of 5, Strong: At least one large randomized trial, or very large consistent studies, on this exact question. How we score
Step by step
For the whole picture, from prevention and screening to treatment and life after, see the breast cancer page.
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